Calcium Citrate Malate (CCM)

Calcium citrate malate is a water-soluble calcium supplement. It is composed of the calcium salt of citric acid and malic acid, with variable composition.

CAS No.: 142606-53-9
Molecular formula : Ca6(C6H5O7)2(C4H4O5)3·6H2O


Calcium Citrate Malate Structure
Calcium Citrate Malate

Calcium Citrate Malate

Bioavailability of CCM is due to its water solubility and dissolution method. When dissolved, it releases calcium ions and a calcium citrate complex. Calcium ions are absorbed directly into intestinal cells, while the citrate complex enters the body through paracellular absorption. The European Food Safety Authority has concluded that calcium citrate malate is “slightly more bioavailable” than other forms of calcium supplementation.

Calcium plays a crucial role in nerve function, cell activity, muscle contraction, and bone health. Vitamin D helps absorb calcium and phosphorus, essential for strong bones & treating the following :

  • Osteoporosis : A condition characterized by bone loss.
  • Osteomalacia / Rickets : Weak bones due to insufficient calcium.
  • Hypoparathyroidism : Decreased activity of the parathyroid gland.
  • Latent Tetany : A certain muscle disease.
Calcium Citrate Malate